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and Miller Y, Insight into a New Binding Site of Zinc Ions in Fibrillar Amylin, ACS Chem

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In about 17,600 adults with overweight or obesity, established cardiovascular disease, and no diabetes, the primary cardiac composite occurred in 6.5% assigned to semaglutide and 8.0% assigned to placebo over roughly 40 months (HR 0.80, 95% CI 0.72–0.90).³ This is a secondary-prevention result in people who already had cardiovascular disease, not a fixed-dose comparison or a general heart-health claim