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Often the missing link in treatment is proper communication with the patient
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This is possible, but given that innate inflammation in the form of microglial activation and macrophage infiltration is a universal response to most types of CNS injury (Rivest, 2009), we would argue that it remains equally plausible that in MS microglia/macrophages are instead reacting to some persistent underlying pathological process in an attempt to limit and repair the expanding white matter damage
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