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Type I collagen is found in healthy skin, whereas type III collagen is what is initially produced by fibroblasts and is a thinner, less mature type of collagen

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For example, in AD research, an FRG signature composed of genes such as DNA damage inducible transcript 4, mucin 1 and CD44 was found to not only distinguish patients with AD from healthy controls but also to predict disease severity and immune cell infiltration in the brain (43)