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The Evolving Role of Selenium in the Treatment of Graves′ Disease and Ophthalmopathy - Duntas - 2012 - Journal of Thyroid Research - Wiley Online Library

That means that even though there seems to be no link between high Vitamin B12 levels and risk of heart diseases, there is enough of a relationship for you to prioritize Vitamin B12-rich foods in your vegetarian/vegan diet to gain full advantage of the many benefits related to heart disease

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Exogenous 4-OI rescues disease even on the Acod1⁻ / ⁻ background, confirming a protective Acod1-itaconate axis