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These solvents, also known as designer solvents, can be synthesized for specific applications, including the extraction of bioactive chemicals ( Deep eutectic solvents are synthesized using various hydrogen bond donors and acceptors, such as choline chloride, menthol, and betaine ( Appropriate dosing significantly influences the biological efficacy of curcumin and turmeric extracts ( Curcumin and turmeric extracts are generally considered nontoxic and highly promising for various biological applications when administered at appropriate doses ( 6 Techniques for curcumin isolation from turmeric rhizomes Turmeric rhizomes contain two main pharmacologically active secondary metabolites: curcuminoids and essential oils ( Traditional techniques include maceration and Soxhlet extraction ( Curcumin can be extracted using thin-layer chromatography (TLC) on the extraction mixture, a traditional analytical method ( The production and stability of curcumin are greatly influenced by the extraction method used

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