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DIHEXA DIHEXA (also recognized in pre-clinical literature as PNB-0408 or ATH-1001) is a synthetic, angiotensin IV-derived peptidomimetic compound engineered to investigate pathways regulating synaptic connectivity and neuroplasticity

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Notably, the apoptotic effects of salusin-β overexpression in these cells were reversed by inhibitors such as Go 6976 (a PKC inhibitor), N-acetylcysteine (a ROS scavenger), apocynin (an NADPH oxidase inhibitor), and pifithrin-α (a p53 inhibitor)