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β -Arr-dependent endocytosis of the GPCR, diminishes signaling, and reduces the number of receptor binding sites in the plasma membrane (Kendall and Luttrell, 2009)

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The dendrogram was cut using cutreeDynamic (deepSplit = 2, minClusterSize = 15, cutHeight = 0.999) and the cut dendrogram merged with mergeCloseModules (cutHeight = 0.15, corFnc = bicor, maxPoutliers = 0.1, pearsonFallback = “individual”)